38 research outputs found

    Content-based Map of Science using Cross-lingual Document Embedding - A Comparison of US-Japan Funded Projects

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    Maps depicting the structure of science help us understand the development of science and technology. However, as it is difficult to apply inter-citation and co-citation analysis to recently published papers and ongoing projects that have few or no references, our previous work developed a content-based map by locating research papers and funding projects using word/document embedding. Because difficulties arise when comparing the content-based map in different languages, this paper improves our content-based map by developing a method for generating multi-dimensional vectors in the same space from cross-lingual (English and Japanese) documents. Using 1,000 IEEE papers, we confirmed a similarity of 0.76 for matching bilingual contents. Finally, we constructed a map from 34,000 projects of the National Science Foundation and Japan Society for the Promotion of Science from 2012 to 2015, and we indicate the findings obtained from a comparison of the US-Japan funded projects

    Synthetic Quantum Systems

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    So far proposed quantum computers use fragile and environmentally sensitive natural quantum systems. Here we explore the new notion that synthetic quantum systems suitable for quantum computation may be fabricated from smart nanostructures using topological excitations of a stochastic neural-type network that can mimic natural quantum systems. These developments are a technological application of process physics which is an information theory of reality in which space and quantum phenomena are emergent, and so indicates the deep origins of quantum phenomena. Analogous complex stochastic dynamical systems have recently been proposed within neurobiology to deal with the emergent complexity of biosystems, particularly the biodynamics of higher brain function. The reasons for analogous discoveries in fundamental physics and neurobiology are discussed.Comment: 16 pages, Latex, 1 eps figure fil

    On Uniqueness of the Jump Process in Quantum Measurement Theory

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    We prove that, contrary to the standard quantum theory of continuous observation, in the formalism of Event Enhanced Quantum Theory the stochastic process generating individual sample histories of pairs (observed quantum system, observing classical apparatus) is unique. This result gives a rigorous basis to the previous heuristic argument of Blanchard and Jadczyk. Possible implications of this result are discussed.Comment: 31 pages, LaTeX, article; e-mail contact [email protected]

    Dissipation and spontaneous symmetry breaking in brain dynamics

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    We compare the predictions of the dissipative quantum model of brain with neurophysiological data collected from electroencephalograms resulting from high-density arrays fixed on the surfaces of primary sensory and limbic areas of trained rabbits and cats. Functional brain imaging in relation to behavior reveals the formation of coherent domains of synchronized neuronal oscillatory activity and phase transitions predicted by the dissipative model.Comment: Restyled, slight changes in title and abstract, updated bibliography, J. Phys. A: Math. Theor. Vol. 41 (2008) in prin

    Magnetism, FeS colloids, and Origins of Life

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    A number of features of living systems: reversible interactions and weak bonds underlying motor-dynamics; gel-sol transitions; cellular connected fractal organization; asymmetry in interactions and organization; quantum coherent phenomena; to name some, can have a natural accounting via physicalphysical interactions, which we therefore seek to incorporate by expanding the horizons of `chemistry-only' approaches to the origins of life. It is suggested that the magnetic 'face' of the minerals from the inorganic world, recognized to have played a pivotal role in initiating Life, may throw light on some of these issues. A magnetic environment in the form of rocks in the Hadean Ocean could have enabled the accretion and therefore an ordered confinement of super-paramagnetic colloids within a structured phase. A moderate H-field can help magnetic nano-particles to not only overcome thermal fluctuations but also harness them. Such controlled dynamics brings in the possibility of accessing quantum effects, which together with frustrations in magnetic ordering and hysteresis (a natural mechanism for a primitive memory) could throw light on the birth of biological information which, as Abel argues, requires a combination of order and complexity. This scenario gains strength from observations of scale-free framboidal forms of the greigite mineral, with a magnetic basis of assembly. And greigite's metabolic potential plays a key role in the mound scenario of Russell and coworkers-an expansion of which is suggested for including magnetism.Comment: 42 pages, 5 figures, to be published in A.R. Memorial volume, Ed Krishnaswami Alladi, Springer 201

    Cytoskeletal Signaling: Is Memory Encoded in Microtubule Lattices by CaMKII Phosphorylation?

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    Memory is attributed to strengthened synaptic connections among particular brain neurons, yet synaptic membrane components are transient, whereas memories can endure. This suggests synaptic information is encoded and ‘hard-wired’ elsewhere, e.g. at molecular levels within the post-synaptic neuron. In long-term potentiation (LTP), a cellular and molecular model for memory, post-synaptic calcium ion (Ca2+) flux activates the hexagonal Ca2+-calmodulin dependent kinase II (CaMKII), a dodacameric holoenzyme containing 2 hexagonal sets of 6 kinase domains. Each kinase domain can either phosphorylate substrate proteins, or not (i.e. encoding one bit). Thus each set of extended CaMKII kinases can potentially encode synaptic Ca2+ information via phosphorylation as ordered arrays of binary ‘bits’. Candidate sites for CaMKII phosphorylation-encoded molecular memory include microtubules (MTs), cylindrical organelles whose surfaces represent a regular lattice with a pattern of hexagonal polymers of the protein tubulin. Using molecular mechanics modeling and electrostatic profiling, we find that spatial dimensions and geometry of the extended CaMKII kinase domains precisely match those of MT hexagonal lattices. This suggests sets of six CaMKII kinase domains phosphorylate hexagonal MT lattice neighborhoods collectively, e.g. conveying synaptic information as ordered arrays of six “bits”, and thus “bytes”, with 64 to 5,281 possible bit states per CaMKII-MT byte. Signaling and encoding in MTs and other cytoskeletal structures offer rapid, robust solid-state information processing which may reflect a general code for MT-based memory and information processing within neurons and other eukaryotic cells

    Electric and Magnetic Fields Inside Neurons and Their Impact Upon the Cytoskeletal Microtubules

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    Comparative analysis of patent-paper citations of five countries based on new indicators

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    We compared the technological impact of five countries—the United States, Japan, Germany, the United Kingdom, and China—using two indicators that we developed—the Patent–Paper Citation Index (PPCI) and the High Feature-Valued Patent–Paper Citation Index (HFPPCI)—and whose reliabilities we validated. First, we analyzed both the scientific and technological impacts of papers using the PPCI in combination with the Normalized Citation Impact. Results revealed the relatively high scientific and technological impacts of the United States in all disciplines and China’s rapid rise of the both impacts. However, PPCI values tended to asymptotically approach average values as the share of papers increased. Second, we analyzed the relative citedness of papers in high-feature-valued patents in terms of patent family size, patent–patent forward citations, and patent generality index—using the HFPPCI. Results showed the relative citedness of each country’s papers with high-feature-valued patents among all papers from the country
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